Correlation between fecal concentrations of ciprofloxacin and fecal counts
نویسندگان
چکیده
towards new means to control the spread of resistance? 3 Thu Thuy Nguyen, Elisabeth Chachaty, Clarisse Huy, Carole Cambier, Jean de 4 Gunzburg, France Mentré and Antoine Andremont 5 University Paris Diderot, Sorbonne Paris Cité, Paris, France; INSERM, UMR 738, Paris, 6 France ; Institut Gustave-Roussy, Paris, France; Da Volterra, Paris, France; University 7 of Liège, Liège, Belgium; EA3964, “Emergence de la résistance bactérienne in vivo”, 8 Paris, France; AP-HP, Hospital Bichat, Paris, France 9
منابع مشابه
Correlation between fecal concentrations of ciprofloxacin and fecal counts of resistant Enterobacteriaceae in piglets treated with ciprofloxacin: toward new means to control the spread of resistance?
We assessed in a piglet model the relationship between fecal ciprofloxacin concentrations and ciprofloxacin-resistant Enterobacteriaceae counts. Twenty-nine piglets were orally treated with placebo or with 1.5 or 15 mg ciprofloxacin/kg of body weight/day from day 1 (D1) to D5. Areas under the curve (AUC) of concentrations increased sharply with dose and correlated positively with AUC of resista...
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